Cancer Research Initiative Publications


  1. FLOT4-AIO Investigators, 2019. Perioperative chemotherapy with fluorouracil plus leucovorin, oxaliplatin, and docetaxel versus fluorouracil or capecitabine plus cisplatin and epirubicin for locally advanced, resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4): a randomised, phase 2/3 trial. Lancet, 393, pp.1948.
  2. Allanson E.R. et al., 2019. Morbidity after surgical management of cervical cancer in low and middle income countries: A Systematic review and meta-analysis. PLoSOne, 14(7):e0217775.
  3. Antel, K. et al., 2019. The determinants and impact of diagnostic delay in lymphoma in a TB and HIV endemic setting. BMC Cancer, 19(1), pp.384.
  4. Berg, C. et al., 2019. Modulation of the solubility properties of arene ruthenium complexes bearing stannyl ligands as potential anti-cancer agents. Journal of Organometallic Chemistry, 891, pp.12-19.
  5. Bhatla, N. et al., 2019. Revised FIGO staging for carcinoma of the cervix uteri. International Journal of Gynecology and Obstetrics, 145(1), pp.129-135.
  6. Bleloch, J. et al., 2019. The palladacycle complex AJ-5 induces apoptotic cell death while reducing autophagic flux in rhabdomyosarcoma cells. Cell Death Discovery, 5, pp.60.
  7. Blumenthal, M.J. et al., 2019. The Contribution of Kaposi's Sarcoma-Associated Herpesvirus to Mortality in Hospitalized Human Immunodeficiency Virus-Infected Patients Being Investigated for Tuberculosis in South Africa. Journal of Infectious Diseases, 220(5), pp.841-851.
  8. Cervenka, B, et al., 2019. Oral cavity cancer management guidelines for low-resource regions. Head and Neck, 41(3), pp.799-812.
  9. Chambuso, R. et al., 2019. Investigation of Cervical Tumor Biopsies for Chromosomal Loss of Heterozygosity (LOH) and Microsatellite Instability (MSI) at the HLAII Locus in HIV-1/HPV co-infected women. Frontiers in Oncology, 9, pp.951.
  10. Cohen, P.A., Jhingran, A., Oaknin, A; & Denny L., 2019. Cervical Cancer. Lancet, 393 (10167), pp.169-182.
  11. Dalvie, S., 2019. Head and neck cancer in Africa. SA Journal of Oncology, 3(0), a67.
  12. Fagan, J.J., Chaturvedi, P. & Kowalski, L.P., 2019. Treatment Options for Hypopharyngeal Cancer in Developing Countries in Africa/South America/Asia: in Bradley PJ, Eckel HE (eds): Hypopharyngeal Cancer. Advances in oto-rhino-laryngology. 83, pp.159-166.
  13. Fagan, J.J. et al., 2019. African Head and Neck Fellowships: A Model for a Sustainable Impact on Head and Neck Cancer Care in Developing Countries Head and Neck. 41(6), pp.1824-1829.
  14. Fagan, J.J., 2019. Open Access Publishing for otolaryngologists in Africa and Developing Countries. OTO Open, 3(3):2473974X19861567.
  15. Fish, M. et al., 2019. POETIC (The Program for Enhanced Training in Cancer): An Initial Experience of Supporting Capacity Building for Oncology Training in Sub-Saharan Africa. The Oncologist, 24(12), pp.1557-1561.
  16. Githaiga, J.N. et al., 2019. Symptom awareness measures for breast and cervical cancer in Sub-Saharan Africa: A scoping review. South African Journal of Oncology, 3(0), a78.
  17. Grobbelaar, S. et el., 2019.  Haematopoietic stem cell transplantation in South Africa: Current limitations and future perspectives.  South African Medical Journal, 109(8b), pp.46-52.
  18. Hess, C.B. et al., 2019. The Pediatric Radiation Oncology Society Working Group on Low- and Middle-Income Countries (PROS-LMIC) Strategic Plan to Advance Care, Education, and Research. International Journal of Radiation Oncology Biology Physics, 105(4), pp.913.
  19. Hussain, A.F. et al., 2019. One step site-specific antibody fragment conjugation using SNAP tag technology. Nature Protocols, 14, pp.3101-3125.
  20. Jenkins, N., Louw, V. & Opie, J.J., 2019.  Images in Hematology: Massive megakaryocyte clustering in triple-negative primary myelofibrosis associated with an unusual cytogenetic aberration.  British Journal of Haematology, 186(4), pp.510.
  21. Kaschula, C.H. et al., 2019. The garlic compound ajoene covalently binds vimentin, disrupts the vimentin network and exerts anti-metastatic activity in cancer cells. BMC Cancer, 19(1), pp.248.
  22. Khan, S.F. et al., 2019. The roles and regulation of TBX3 in development and disease, Gene, 726, pp. 144223.
  23. Kisling, K. et al., 2019. A risk assessment of automated treatment planning and recommendations for clinical deployment. Medical Physics, 46(6).
  24. Kisling, K., Zhang, L., Shaitelman, S.F. & Anderson, D., 2019. Automated treatment planning of postmastectomy radiotherapy. Med Phys. 46 (9), pp.2567-2574.
  25. Kisling, K., Zhang, L., Simonds, H. & Fakie, N., 2019. Fully Automatic Treatment Planning for External-Beam Radiation Therapy of Locally Advanced Cervical Cancer: A Tool for Low-Resource Clinics. Journal of Global Oncology, 5, pp.1-9.
  26. Lubbe, D. et al., 2019. Transorbital Endoscopic Surgery. Current Otorhinolaryngology Reports, 7, pp.173-180. 
  27. Ludmir, E. et al., 2019. Assembling the Brain Trust: The Multidisciplinary Imperative in Neuro-Oncology. Nature reviews in Clinical Oncology, 16(8), pp.521-522.
  28. Mapekula, L., Romarola, B.R., Goolam Hoosen, T. & Mowla, S., 2019. The interplay between viruses & host microRNAs in cancer – An emerging role for HIV in oncogenesis. Critical Reviews in Oncology / Hematology, 137, pp.108-114.
  29. McGuire, J.K., Lentin, R., De Villiers, A. & Fagan, J.J., 2019. Pharyngoesophageal spasm after total laryngectomy: A clinically guided technique for management. East and Central African Journal of Surgery, 24(3).
  30. McGuire, J.K. et al., 2019. Does Thyroid Gland Preserving Total Laryngectomy Affect Oncological Control in Laryngeal Carcinoma? Laryngoscope, 130(6):1465-1469.
  31. Moodley, J. et al., 2019. Exploring the feasibility of using mobile phones to improve the management of cervical cancer precursor lesions. BMC Women’s Health, 19(1), pp.2.
  32. Moodley, J. et al., 2019. Development and validation of the African Women Awareness of CANcer (AWACAN) tool for breast and cervical cancer. PLoS ONE 14(8): e0220545.
  33. Mungra, N. et al., 2019. Targeted human cytolytic fusion proteins at the cutting edge: harnessing the apoptosis-inducing properties of human enzymes for the selective elimination of tumor cells. Oncotarget, 10(8), pp.897-915.
  34. Nachreiner, I. et al, 2019. Elimination of Her3-expressing breast cancer cells using aptamer-iRNA chimeras. Experimental and Therapeutic Medicne, 18(4), pp.2401-2412.
  35. Omar, R. et al., 2019. COL1A2 is a bona fide TBX3 target that mediates its impact on fibrosarcoma and chondrosarcoma cell migration. Cancer Letters, 459, pp. 227-239.
  36. Padayachee, E.R. et al, 2019. Applications of SNAP-tag technology in skin cancer therapy. Health Science Reports, 2(2), e103.
  37. Pickard, H.D.P. et al, 2019. The management of desmoid tumours at Groote Schuur Hospital retrospective review of current practice. South African Journal of Oncology, 3, a68.
  38. SOLE Investigators, 2019. Quality of life under extended continuous versus intermittent adjuvant letrozole in lymph node-positive, early breast cancer patients: the SOLE randomised phase 3 trial. British Journal of Cancer, 120(10), pp.959-967.
  39. Scott, A.J. et al., 2019. Quality of life after total laryngectomy: evaluating the effect of socioeconomic status. Journal of Laryngology and Otology, 133(2), pp.129-134.
  40. Swart, L., Novitzky, N., Mohamed, Z. & Opie, J., 2019. Hodgkin lymphoma at Groote Schuur Hospital, South Africa: the effect of HIV and bone marrow infiltration.  Annals of Hematology, 98: 381-389.
  41. Tomaisichio, M. et el., 2019.  An autologous dentritic cell vaccine polarizes a Th-1 response which is tumoricidal to patient-derived breast cancer cells. Cancer Immunology, Immunotherapy, 68, pp.71-83.
  42. Ujma, S. et al., 2019. Surfactant Protein A Impairs Genital HPV16 Pseudovirus Infection by Innate Immune Cell Activation in A Murine Model. Pathogens, 8(4), pp.288.
  43. van Schalkwyk, C., Moodley, J., Welte, A. & Johnson, L.F., 2019. Estimated impact of human papillomavirus vaccines on infection burden: the effect of structural assumptions. Vaccine, 37(36), pp.5460-546.
  44. van Schalkwyk, C., Moodley, J., Welte, A. & Johnson, L.F., 2019.  Are associations between HIV and human papillomavirus transmission due to behavioural confounding or biological effects? Sexually Transmitted Infections, 95, pp.122-128.
  45. Vaughan, C.L. Novel imaging approaches to screen for breast cancer: Recent advances and future prospects. Medical Engineering and Physics, 72, pp.27-37.