IBC Institutional Biosafety Committee (Senate-Level Committee responsible for Biosafety and GMO Approvals)
FBC Faculty Biosafety Committee (FHS, Science, and EBE each maintain an FBC)
HREC Human Research Ethics Committee
AEC Animal Ethics Committee
PI Principal Investigator
pHBAs Potentially Hazardous Biological Agents
GMOs Genetically Modified Organisms
Why do I need Biosafety (F/IBC) approval?
üIt is UCT’s institutional policy that all research involving genetically modified organisms (GMOs), recombinant or synthetic nucleic acid molecules and potentially hazardous biological agents (pHBAs) must be approved by the F/IBC.
üThe full IBC policy document is available here.
üThe IBC Terms of Reference are available here
Can I commence research involving recombinant DNA and potentially hazardous biological agents before getting F/IBC approval?
üNo. All research involving recombinant or synthetic nucleic acid molecules or pHBAs must be approved by the F/IBC before work can be initiated.
üNote that F/IBC approval cannot be given retrospectively.
When can I start my research?
üOnly after your research protocol has received F/IBC approval, in addition to any other required approvals such as HREC, where needed.
What forms and supporting documents do I need to complete?
How long does it take for FBC to review a protocol?
The FBC aims to review all proposals within 3 weeks of receipt; review comments are returned to the applicant and, following revision/correction, the revised application will be re-circulated among the FBC. Generally, the re-review is faster, and a decision letter will be issued within two weeks of submission of the revised proposal. Depending on the type of project, escalation to the IBC for final review and approval may be required.
How often do I have to renew my protocol?
The PI is required to submit an Annual Progress Report on active projects to the FBC
Do I still need approvals from other committees such as HREC, AEC?
Yes, having FBC approval does not exempt you from other required institutional and national approvals. It is recommended that you submit your FBC application prior to, or concurrent with, your HREC or AEC and/or DAFF Section 20 permit applications if your research protocol involves humans or animals, respectively. Please refer to their respective webpages for the required paperwork.
Can I make changes to my project post FBC approval?
Yes – kindly submit to the FBC an amendment application which can be found on the FHS FBC webpage