PhD study in the Institute of Infectious Disease & Molecular Medicine
The European & Developing Countries Clinical Trials Partnership (EDCTP) has awarded a research grant to the coordinator (A/Prof. Reto Guler) of the international consortium “PravaTB” for a 4-year project to evaluate the safety and efficacy of pravastatin to reduce inflammation after tuberculosis treatment. This projects includes the investigation of immunological and blood biomarkers, blood transcriptional and proteomic profiling by ELISA/luminex, RNAseq, mass spectrometry and macrophage assays (phagosomal, autophagy and ex vivo M. tuberculosis growth) of study participants. This fellowship aims to recruit a talented candidate to pursue PhD in the research group of A/Prof. Reto Guler starting 21 February 2019.
- Applicants may not previously have held full-time professional or academic posts.
- No service or services is required in return for the fellowship.
- The successful incumbent will be required to comply with the University’s approved policies, procedures and practices for the doctoral sector.
Value and tenure
- The value of the fellowship is R 180’000 per annum with secured funding for 4 years.
- The value of the fellowship will increase in the second year and subsequent years.
- Renewal for the second year and subsequent years will be considered on evidence of satisfactory academic progress.
- The fellowship is in accordance with the SARS Guidelines is tax-exempt.
- This fellowship seeks to attract outstanding candidates with a strong work ethics that are self-motivated and driven.
- Ability to work under pressure subject to deadlines and high professional and academic standards.
- This fellowship is only available to individuals who have achieved the master degree and graduated in Molecular and Cell Biology, Immunology or Biochemistry.
- The doctoral research fellow (DRF) will be directly responsible to A/Prof. Reto Guler.
- Dr. Guler will provide the operational research costs from his EDCTP grant.
- All necessary equipment and laboratory spaces are in place to meet the demands of the project.
- The applicant will be required to write SOPs and will be responsible for specimen storage and sample analysis.
- The applicant will work in close association with the clinical trial group and must be on standby, reachable by WhatsApp Messenger, when valuable specimens arrive in the lab for processing and analyzing.
- Applicant should be actively involved in research in “Immunology of Infectious Diseases” and have experience and/or interest in clinical immunology with skills in PBMC isolation, generation of monocyte-derived human macrophages, molecular biology and standard immunological techniques. As part of their professional development, candidates must participate in weekly departmental activities including Progress Reports and Journal Club presentations.
- Previous exposure to clinical work and received GCP training is recommended but not necessary.
All applications should include:
- A letter of motivation stating the applicant’s areas of expertise, research interests and experience.
- A CV including a list of publications and details of acquired laboratory techniques.
- One or two reference letter from academics, who have taught, supervised or worked alongside the applicant.
- If you do not receive feedback within six weeks of the deadline, please assume that your application has not been successful.
Applications should be directly emailed to Principal Investigator A/Prof. Reto Guler (firstname.lastname@example.org) before 7 February 2018.
The University of Cape Town reserves the right to disqualify ineligible, incomplete and/or inappropriate applications. The University of Cape Town reserves the right to change the conditions of award or to make no awards at all.