Cancer Research Initiative Publications


  1. Adler, D.H., Laher, F., Lazarus, E., Grzesik, K., Gray, G.E., Allan, B. & Williamson, A. 2013. A Viable and Simple Self-Sampl ing Method for Human Papillomavirus Detection among South African Adolescents. Journal of Immunological Techniques in Infectious Diseases. 2(3).

  2. Arbyn, M., de Sanjosé, S., Saraiya, M., Sideri, M., Palefsky, J., Lacey, C., Gillison, M., Bruni, L. et al. 2012. EUROGIN 2011 roadmap on prevention and treatment of HPV‐related disease. International Journal of Cancer. 131(9):1969-1982.

  3. Ballim, R.D., Mendelsohn, C., Papaioannou, V.E. & Prince, S. 2012. The ulnar-mammary syndrome gene, Tbx3, is a direct target of the retinoic acid signaling pathway, which regulates its expression during mouse limb development. Molecular Biology of the Cell. 23(12):2362-2372. DOI:10.1091/mbc.E11-09-0790; 10.1091/mbc.E11-09-0790.

  4. Boér, K., Láng, I., Llombart-Cussac, A., Andreasson, I., Vivanco, G.L., Sanders, N., Pover, G.M. & Murray, E. 2012. Vandetanib with docetaxel as second-line treatment for advanced breast cancer: a double-blind, placebo-controlled, randomized Phase II study. Investigational New Drugs. 30(2):681-687.

  5. Bohm, L., Serafin, A., Fernandez, P., Van der Watt, G., Bouic, P. & Harvey, J. 2012. Plasma sarcosine does not distinguish early and advanced stages of prostate cancer. SAMJ: South African Medical Journal. 102(8):677-679.

  6. Breytenbach, J.C., Denti, P., Kolesnikova, N., Lombard, M.C., N'da, D.D., Norman, J., Vial, H., Wein, S. et al. 2012. Antimalarial and anticancer activities of artemisinin-quinoline hybrid-dimers and pharmacokinetic properties in mice.

  7. Bye, H., Prescott, N.J., Lewis, C.M., Matejcic, M., Moodley, L., Robertson, B., Rensburg, C., Parker, M.I. et al. 2012. Distinct genetic association at the PLCE1 locus with oesophageal squamous cell carcinoma in the South African population. Carcinogenesis. 33(11):2155-2161. DOI:10.1093/carcin/bgs262; 10.1093/carcin/bgs262.

  8. Chellan, P., Land, K.M., Shokar, A., Au, A., An, S.H., Clavel, C.M., Dyson, P.J., Kock, C.d. et al. 2012. Exploring the versatility of cycloplatinated thiosemicarbazones as antitumor and antiparasitic agents. Organometallics. 31(16):5791-5799.

  9. Chetty, R., Gill, P., Govender, D., Bateman, A., Chang, H.J., Deshpande, V., Driman, D., Gomez, M. et al. 2012. International study group on rectal cancer regression grading: interobserver variability with commonly used regression grading systems. Human Pathology. 43(11):1917-1923.

  10. Chetty, R., Gill, P., Govender, D., Bateman, A., Chang, H.J., Driman, D., Duthie, F., Gomez, M. et al. 2012. A multi-centre pathologist survey on pathological processing and regression grading of colorectal cancer resection specimens treated by neoadjuvant chemoradiation. Virchows Archiv. 460(2):151-155.

  11. Costamagna, G., Tringali, A., Spicak, J., Mutignani, M., Shaw, J., Roy, A., Johnsson, E., De Moura, E.G. et al. 2012. Treatment of malignant gastroduodenal obstruction with a nitinol self-expanding metal stent: an international prospective multicentre registry. Digestive and Liver Disease. 44(1):37-43.

  12. Denny, L. 2012. Cervical cancer prevention: New opportunities for primary and secondary prevention in the 21st century. International Journal of Gynecology & Obstetrics. 119:S80-S84.

  13. Denny, L. 2012. Cytological screening for cervical cancer prevention. Best Practice & Research Clinical Obstetrics & Gynaecology. 26(2):189-196.

  14. Denny, L.A., Franceschi, S., de Sanjosé, S., Heard, I., Moscicki, A.B. & Palefsky, J. 2012. Human papillomavirus, human immunodeficiency virus and immunosuppression. Vaccine. 30:F168-F174.

  15. Denny, L. & Anorlu, R. 2012. Cervical cancer in Africa. Cancer Epidemiology, Biomarkers & Prevention : A Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. 21(9):1434-1438. DOI:10.1158/1055-9965.EPI-12-0334; 10.1158/1055-9965.EPI-12-0334.

  16. Duncan, K., Schäfer, G., Vava, A., Parker, M.I. & Zerbini, L.F. 2012. Targeting neddylation in cancer therapy. Future Oncology. 8(11):1461-1470.

  17. Duncan, K., Uwimpuhwe, H., Czibere, A., Sarkar, D., Libermann, T.A., Fisher, P.B. & Zerbini, L.F. 2012. NSAIDs induce apoptosis in nonproliferating ovarian cancer cells and inhibit tumor growth in vivo. IUBMB Life. 64(7):636-643.

  18. Dzobo, K., Leaner, V.D. & Parker, M.I. 2012. Feedback regulation of the α2 (1) collagen gene via the Mek-Erk signaling pathway. IUBMB Life. 64(1):87-98.

  19. Eklund, C., Forslund, O., Wallin, K.L., Zhou, T., Dillner, J. & WHO Human Papillomavirus Laboratory Network 2012. The 2010 global proficiency study of human papillomavirus genotyping in vaccinology. Journal of Clinical Microbiology. 50(7):2289-2298.

  20. England, R., Pillay, K., Davidson, A., Numanoglu, A. & Millar, A. 2012. Intussusception as a presenting feature of Burkitt lymphoma: implications for management and outcome. Pediatric Surgery International. 28(3):267-270.

  21. Geeleher, P., Huang, S.R., Gamazon, E.R., Golden, A. & Seoighe, C. 2012. The regulatory effect of miRNAs is a heritable genetic trait in humans. BMC Genomics. 13(1):383.

  22. Govender, D. & Chetty, R. 2012. Gene of the month: BRAF. Journal of Clinical Pathology. 65(11):986-988. DOI:10.1136/jclinpath-2012-200960; 10.1136/jclinpath-2012-200960.

  23. Govender, D. & Chetty, R. 2012. Gene of the month: PTEN. Journal of Clinical Pathology. 65(7):601-603. DOI:10.1136/jclinpath-2012-200711; 10.1136/jclinpath-2012-200711.

  24. Govender, D., Serra, S. & Chetty, R. 2012. Collision tumor of the stomach: an unusual combination of adenocarcinoma and immature "neuroepitheliomatous" teratoma. International Journal of Surgical Pathology. 20(5):507-510.

  25. Harris, T., Peer, S. & Fagan, J. 2012. Audiological monitoring for ototoxic tuberculosis, human immunodeficiency virus and cancer therapies in a developing world setting. The Journal of Laryngology & Otology. 126(06):548-551.

  26. Hunter, A. 2012. Radiation biology: an important science for an advanced nuclear nation like South Africa. South African Journal of Science. 108(7-8):33-43.

  27. Kabir, F., Van Gelderen, C., McIntyre, J., Michelow, P., Turton, D. & Adam, Y. 2012. Cervical intra-epithelial neoplasia in HIV-positive women after excision of the transformation zone-does the grade change? SAMJ: South African Medical Journal. 102(9):757-760.

  28. Kaschula, C.H., Hunter, R., Stellenboom, N., Caira, M.R., Winks, S., Ogunleye, T., Richards, P., Cotton, J. et al. 2012. Structure-activity studies on the anti-proliferation activity of ajoene analogues in WHCO1 oesophageal cancer cells. European Journal of Medicinal Chemistry. 50:236-254.

  29. Kew, M.C. 2012. Hepatitis B virus/human immunodeficiency virus co-infection and its hepatocarcinogenic potential in sub-saharan black africans. Hepatitis Monthly. 12(10 HCC).

  30. Latib, A., Montorfano, M., Figini, F., Maisano, F., Chieffo, A., Benussi, S., Bellanca, R., Gerli, C. et al. 2012. Percutaneous valve replacement in a young adult for radiation-induced aortic stenosis. Journal of Cardiovascular Medicine (Hagerstown, Md.). 13(6):397-398.

  31. Lawson, A., Beningfield, S., Krige, J., Rischbieter, P. & Burmeister, S. 2012. Percutaneous transhepatic self-expanding metal stents for palliation of malignant biliary obstruction: general surgery. South African Journal of Surgery. 50(3):54-60.

  32. Loubser, F., de Villiers, J. & van der Merwe, N. 2012. Two double heterozygotes in a South African Afrikaner family: implications for BRCA1 and BRCA2 predictive testing. Clinical Genetics. 82(6):599-600.

  33. Lubbe, D., Fisher-Jeffes, N. & Semple, P. 2012. Endoscopic resection of skull base tumours utilising the ultrasonic dissector. The Journal of Laryngology & Otology. 126(06):625-629.

  34. Mathers, J.C., Movahedi, M., Macrae, F., Mecklin, J., Moeslein, G., Olschwang, S., Eccles, D., Evans, G. et al. 2012. Long-term effect of resistant starch on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial. The Lancet Oncology. 13(12):1242-1249.

  35. Mbulawa, Z.Z., Marais, D.J., Johnson, L.F., Coetzee, D. & Williamson, A.L. 2012. Impact of human immunodeficiency virus on the natural history of human papillomavirus genital infection in South African men and women. The Journal of Infectious Diseases. 206(1):15-27.

  36. McDonald, A.C., Denny, L., Wang, C., Tsai, W., Wright Jr, T.C. & Kuhn, L. 2012. Distribution of high-risk human papillomavirus genotypes among HIV-negative women with and without cervical intraepithelial neoplasia in South Africa. PloS One. 7(9):e44332.

  37. Meiring, T.L., Salimo, A.T., Coetzee, B., Maree, H.J., Moodley, J., Hitzeroth, I.I., Freeborough, M., Rybicki, E.P. et al. 2012. Next-generation sequencing of cervical DNA detects human papillomavirus types not detected by commercial kits. Virol J. 9(164):422X-9.

  38. Meisner, S., González-Huix, F., Vandervoort, J.G., Repici, A., Xinopoulos, D., Grund, K.E. & Goldberg, P. 2012. Self-Expanding Metal Stenting for Palliation of Patients with Malignant Colonic Obstruction: Effectiveness and Efficacy on 255 Patients with 12-Month's Follow-up. Gastroenterology Research and Practice. 2012.

  39. Mendenhall, W.M., Ferlito, A., Takes, R.P., Bradford, C.R., Corry, J., Fagan, J.J., Rinaldo, A., Strojan, P. et al. 2012. Cutaneous head and neck basal and squamous cell carcinomas with perineural invasion. Oral Oncology. 48(10):918-922.

  40. Novitzky, N. & Thomas, V. 2012. In the absence of clinically significant graft vs. host disease, myeloablative conditioning may allow an effective graft vs. leukaemia effect. Leukemia Research. 36(1):104-109.

  41. Panieri, E. 2012. Breast cancer screening in developing countries. Best Practice & Research Clinical Obstetrics & Gynaecology. 26(2):283-290.

  42. Robertson, B., Shepherd, L., Abratt, R., Hunter, A. & Goldberg, P. 2012. Treatment of carcinoma of the anal canal at Groote Schuur Hospital. SAMJ: South African Medical Journal. 102(6):559-561.

  43. Sales, K.J. & Katz, A.A. 2012. Inflammatory pathways in cervical cancer-the University of Cape Town's contribution. SAMJ: South African Medical Journal. 102(6):493-496.

  44. Sales, K.J., Sutherland, J.R., Jabbour, H.N. & Katz, A.A. 2012. Seminal plasma induces angiogenic chemokine expression in cervical cancer cells and regulates vascular function. Biochimica Et Biophysica Acta (BBA)-Molecular Cell Research. 1823(10):1789-1795.

  45. Schwartzberg, L.S., Jacobs, P., Matsouka, P., Azevedo, W. & Pinto, A. 2012. The role of second-generation 5-HT(3) receptor antagonists in managing chemotherapy-induced nausea and vomiting in hematological malignancies. Critical Reviews in oncology/hematology. 83(1):59-70.

  46. Setshedi, M., Epstein, D., Winter, T.A., Myer, L., Watermeyer, G. & Hift, R. 2012. Use of thiopurines in the treatment of inflammatory bowel disease is associated with an increased risk of non‐melanoma skin cancer in an at‐risk population: A cohort study. Journal of Gastroenterology and Hepatology. 27(2):385-389.

  47. Shamley, D., Lascurain-Aguirrebeña, I., Oskrochi, R. & Srinaganathan, R. 2012. Shoulder morbidity after treatment for breast cancer is bilateral and greater after mastectomy. Acta Oncologica. 51(8):1045-1053.

  48. Shapiro, S., Farmer, R.D., Stevenson, J.C., Burger, H.G. & Mueck, A.O. 2012. Does hormone replacement therapy cause breast cancer? An application of causal principles to three studies. Part 4: the Million Women Study. The Journal of Family Planning and Reproductive Health Care / Faculty of Family Planning & Reproductive Health Care, Royal College of Obstetricians & Gynaecologists. 38(2):102-109.

  49. Sharma, K.V. & Davids, L.M. 2012. Depigmentation in melanomas increases the efficacy of hypericin-mediated photodynamic-induced cell death. Photodiagnosis and Photodynamic Therapy. 9(2):156-163.

  50. Sharma, K.V. & Davids, L.M. 2012. Hypericin‐PDT‐induced rapid necrotic death in human squamous cell carcinoma cultures after multiple treatment. Cell Biology International. 36(12):1261-1266.

  51. Singh, P., Raj, R., Bhargava, G., Hendricks, D.T., Handa, S., Slaughter, L.M. & Kumar, V. 2012. β-Lactam synthon-interceded diastereoselective synthesis of functionalized octahydroindole-based molecular scaffolds and their in vitro cytotoxic evaluation. European Journal of Medicinal Chemistry. 58:513-518.

  52. Skelton, M., Kew, M.C. & Kramvis, A. 2012. Distinct mutant hepatitis B virus genomes, with alterations in all four open reading frames, in a single South African hepatocellular carcinoma patient. Virus Research. 163(1):59-65.

  53. Sutherland, J.R., Sales, K.J., Jabbour, H.N. & Katz, A.A. 2012. Seminal plasma enhances cervical adenocarcinoma cell proliferation and tumour growth in vivo. PloS One. 7(3):e33848.

  54. Switala, J.R., Hendricks, M. & Davidson, A. 2012. Serum ferritin is a cost-effective laboratory marker for hemophagocytic lymphohistiocytosis in the developing world. Journal of Pediatric hematology/oncology. 34(3):e89-92.

  55. Tamura, R.E., de Vasconcellos, J.F., Sarkar, D., Libermann, T.A., Fisher, P.B. & Zerbini, L.F. 2012. GADD45 proteins: central players in tumorigenesis. Current Molecular Medicine. 12(5):634-651.

  56. Vaughan, C.L. & Evans, M.D. 2012. Diagnosing breast cancer: An opportunity for innovative engineering. SAMJ: South African Medical Journal. 102(6):562-564.

  57. Vogelsang, M., Wang, Y., Veber, N., Mwapagha, L.M. & Parker, M.I. 2012. The cumulative effects of polymorphisms in the DNA mismatch repair genes and tobacco smoking in oesophageal cancer risk. PloS One. 7(5):e36962.

  58. Wiebe, E., Denny, L. & Thomas, G. 2012. Cancer of the cervix uteri. International Journal of Gynecology & Obstetrics. 119:S100-S109.

  59. Wood, R., Lazarus, J., Davidson, A., Alexander, A., Numanoglu, A. & Millar, A. 2012. Genitourinary rhabdomyosarcoma: lessons from a developing-world series. Journal of Pediatric Surgery. 47(11):2083-2086.

  60. Woolner, A.F., Davidson, A., Skinner, R. & King, D. 2012. Evaluation of Infection Control Advice for Patients at Risk of Chemotherapy-Induced Neutropenia in 2 Pediatric Oncology Centers: Cape Town, South Africa, and Newcastle-Upon-Tyne, UK. Pediatric Hematology-Oncology. 29(1):73-84.

  61. Wright, C.Y., Norval, M., Summers, B., Davids, L., Coetzee, G. & Oriowo, M.O. 2012. The impact of solar ultraviolet radiation on human health in sub-Saharan Africa. South African Journal of Science. 108(11-12):45-51.