Cancer Research Initiative Publications


  1. Adefuye A, Katz AA, Sales KJ. The regulation of inflammatory pathways and infectious disease of the cervix by seminal fluid. Pathology research international 2014;2014.
  2. Adefuye AO, Sales KJ, Katz AA. Seminal plasma induces the expression of IL-1alpha in normal and neoplastic cervical cells via EP2/EGFR/PI3K/AKT pathway. J Mol Signal 2014 Aug 8;9:8-2187-9-8. eCollection 2014. 
  3. Adler DH, Wallace M, Bennie T, Mrubata M, Abar B, Meiring TL, et al. Cervical dysplasia and high-risk human papillomavirus infections among HIV-infected and HIV-uninfected adolescent females in South Africa. Infect Dis Obstet Gynecol 2014;2014.
  4. Aebi S, Gelber S, Anderson SJ, Láng I, Robidoux A, Martín M, et al. Chemotherapy for isolated locoregional recurrence of breast cancer (CALOR): a randomised trial. The Lancet Oncology 2014;15(2):156-163.
  5. Alleyne-Mike K, Mohamed K, Abratt R. Unscheduled visits to the oncology outpatient department: a guide for improving the efficiency of the health care framework. Journal Africain du Cancer/African Journal of Cancer 2014;6(1):32-39.
  6. Angus L, van der Watt PJ, Leaner VD. Inhibition of the nuclear transporter, Kpnbeta1, results in prolonged mitotic arrest and activation of the intrinsic apoptotic pathway in cervical cancer cells. Carcinogenesis 2014 May;35(5):1121-1131.
  7. Beckenkamp A, Santana DB, Bruno AN, Calil LN, Casali EA, Paccez JD, et al. Ectonucleotidase expression profile and activity in human cervical cancer cell lines. Biochemistry and Cell Biology 2014;92(2):95-104.​ 
  8.  Beeton‐Kempen N, Duarte J, Shoko A, Serufuri J, John T, Cebon J, et al. Development of a novel, quantitative protein microarray platform for the multiplexed serological analysis of autoantibodies to cancer‐testis antigens. International Journal of Cancer 2014;135(8):1842-1851.​
  9. Bere A, Tayib S, Kriek J, Masson L, Jaumdally SZ, Barnabas SL, et al. Altered phenotype and function of NK cells infiltrating Human Papillomavirus (HPV)-associated genital warts during HIV infection. Clinical Immunology 2014;150(2):210-219.​
  10. Bohlius J, Valeri F, Maskew M, Prozesky H, Garone D, Sengayi M, et al. Kaposi's Sarcoma in HIV‐infected patients in South Africa: Multicohort study in the antiretroviral therapy era. International Journal of Cancer 2014;135(11):2644-2652.​
  11. Bruwer Z, Algar U, Vorster A, Fieggen K, Davidson A, Goldberg P, et al. Predictive genetic testing in children: constitutional mismatch repair deficiency cancer predisposing syndrome. Journal of genetic counseling 2014;23(2):147-155. 
  12. Cabrera-Fuentes HA, Ruiz-Meana M, Simsekyilmaz S, Kostin S, Inserte J, Saffarzadeh M, et al. RNase1 prevents the damaging interplay between extracellular RNA and tumour necrosis factor-alpha in cardiac ischaemia/reperfusion injury. Thromb Haemost 2014 Dec;112(6):1110-1119.
  13. Checkley W, Ghannem H, Irazola V, Kimaiyo S, Levitt NS, Miranda JJ, et al. Management of NCD in low-and middle-income countries. Global heart 2014;9(4):431-443.
  14. Chellan P, Land KM, Shokar A, Au A, An SH, Taylor D, et al. Synthesis and evaluation of new polynuclear organometallic Ru (II), Rh (III) and Ir (III) pyridyl ester complexes as in vitro antiparasitic and antitumor agents. Dalton Transactions 2014;43(2):513-526.
  15. Cox SG, Kilborn T, Pillay K, Davidson A, Millar AJ. Magnetic resonance imaging versus histopathology in Wilms tumor and nephroblastomatosis: 3 examples of noncorrelation. J Pediatr Hematol Oncol 2014 Mar;36(2):e81-4.
  16. Dachs R, Horn A, Koornhof H, de Jager L, Maqungo S, Roche S. Double pathology, sarcoidosis associated with multiple myeloma: A case report. Journal of Bone Oncology 2014 5;3(2):61-65.​ 
  17. Davidson A, Wainwright RD, Stones DK, Kruger M, Hendricks M, Geel J, et al. Malignancies in South African children with HIV. J Pediatr Hematol Oncol 2014 Mar;36(2):111-117.​ 
  18. Denny L, Adewole I, Anorlu R, Dreyer G, Moodley M, Smith T, et al. Human papillomavirus prevalence and type distribution in invasive cervical cancer in sub‐Saharan Africa. International journal of cancer 2014;134(6):1389-1398.
  19. Diom E, Fagan J, Govender D. Giant Cystic Parathyroid Adenoma Masquerading as a Retropharyngeal Abscess. Otolaryngology 2014;4(154):2.
  20. Djansugurova, L. et al., 2014. Association of DCC, MLH1, GSTT1, GSTM1, and TP53 gene polymorphisms with colorectal cancer in Kazakhstan. Tumor Biology, 36(1), pp.279–289.
  21. Du Toit, J. et al., 2014. Orbital lymphomatoid granulomatosis – a rare cause of proptosis. Pediatric Radiology, 45(7), pp.1095–1098.
  22. Dzobo K, Leaner VD, Parker MI. Absence of feedback regulation in the synthesis of COL1A1. Life Sci 2014;103(1):25-33.
  23. Edge J, Buccimazza I, Cubasch H, Panieri E. The challenges of managing breast cancer in the developing world-a perspective from sub-Saharan Africa. SAMJ: South African Medical Journal 2014;104(5):377-379.
  24. Francis VA, Abera AB, Matjila M, Millar RP, Katz AA. Kisspeptin regulation of genes involved in cell invasion and angiogenesis in first trimester human trophoblast cells. 2014.
  25. Franz DN, Belousova E, Sparagana S, Bebin EM, Frost M, Kuperman R, et al. Everolimus for subependymal giant cell astrocytoma in patients with tuberous sclerosis complex: 2-year open-label extension of the randomised EXIST-1 study. The Lancet Oncology 2014;15(13):1513-1520.
  26. Gordon C. Papshop: Not a'melon'choly Pap smear workshop! SAMJ: South African Medical Journal 2014;104(9):640-640.
  27. Hadley KE, Hendricks DT. Use of NQO1 status as a selective biomarker for oesophageal squamous cell carcinomas with greater sensitivity to 17-AAG. BMC Cancer 2014 May 15;14:334-2407-14-334. 
  28. Hanks S, Perdeaux ER, Seal S, Ruark E, Mahamdallie SS, Murray A, et al. Germline mutations in the PAF1 complex gene CTR9 predispose to Wilms tumour. Nature communications 2014;5.
  29. Harding R, Albertyn R, Sherr L, Gwyther L. Pediatric palliative care in sub-Saharan Africa: a systematic review of the evidence for care models, interventions, and outcomes. J Pain Symptom Manage 2014;47(3):642-651.​ 
  30. Harding R, Selman L, Ali Z, Powell RA, Namisango E, Mwangi-Powell F, et al. Wellbeing among sub-Saharan African patients with advanced HIV and/or cancer: an international multicentred comparison study of two outcome measures. Health and quality of life outcomes 2014;12(1):1-8.
  31. Hartwig K, Dean M, Hartwig K, Mmbando PZ, Sayed A, Vries Ed. Where there is no morphine: The challenge and hope of palliative care delivery in Tanzania. African Journal of Primary Health Care & Family Medicine 2014;6(1):1-8.​
  32. Karampelas T, Argyros O, Sayyad N, Spyridaki K, Pappas C, Morgan K, et al. GnRH-gemcitabine conjugates for the treatment of androgen-independent prostate cancer: pharmacokinetic enhancements combined with targeted drug delivery. Bioconjug Chem 2014;25(4):813-823.
  33. Kew MC. The role of cirrhosis in the etiology of hepatocellular carcinoma. Journal of gastrointestinal cancer 2014;45(1):12-21.
  34. Kleemann B, Loos B, Scriba TJ, Lang D, Davids LM. St John's Wort (Hypericum perforatum L.) photomedicine: hypericin-photodynamic therapy induces metastatic melanoma cell death. 2014.
  35. Krige J, Bernon M, Beningfield S. Modern management of colorectal liver metastases. CE: Your SA Journal of CPD: General surgery 2013;31(6):197-200.
  36. Kruger M, Hendricks M, Davidson A, Stefan CD, van Eyssen AL, Uys R, et al. Childhood cancer in Africa. Pediatric blood & cancer 2014;61(4):587-592. ​
  37. Learmonth G, Learmonth D. Abnormal cervical cytology requiring colposcopy among women under the age of 30 years in the Western Cape Province, South Africa. S Afr J Obstet Gynaecol 2014;20(2):51-53.​
  38. Li J, Ballim D, Rodriguez M, Cui R, Goding CR, Teng H, et al. The anti-proliferative function of the TGF-beta1 signaling pathway involves the repression of the oncogenic TBX2 by its homologue TBX3. J Biol Chem 2014 Dec 19;289(51):35633-35643. 
  39. Mahomed N, Naidoo J, Dlangamandla S, Andronikou S, Pather S, Pillay K. Atypical teratoid/rhabdoid tumour in a supratentorial location: A report of two cases. South African Journal of Child Health 2014;8(4):159-161.
  40. Marco C, Pillay R, Schoonheim C. The management of breast cancer-related lymphoedema. SAMJ: South African Medical Journal 2014;104(5):382-382.
  41. Mbulawa ZZ, Johnson LF, Marais DJ, Gustavsson I, Moodley JR, Coetzee D, et al. Increased alpha-9 human papillomavirus species viral load in human immunodeficiency virus positive women. BMC Infect Dis 2014 Jan 31;14:51-2334-14-51.
  42. McDonald AC, Tergas AI, Kuhn L, Denny L, Wright Jr TC. Distribution of human papillomavirus genotypes among HIV-positive and HIV-negative women in Cape Town, South Africa. Frontiers in oncology 2014;4.
  43. Melis M, Diaz G, Kleiner DE, Zamboni F, Kabat J, Lai J, et al. Viral expression and molecular profiling in liver tissue versus microdissected hepatocytes in hepatitis B virus-associated hepatocellular carcinoma. J Transl Med 2014 Aug 21;12:230-014-0230-1.
  44. Mello Pde A, Filippi-Chiela EC, Nascimento J, Beckenkamp A, Santana DB, Kipper F, et al. Adenosine uptake is the major effector of extracellular ATP toxicity in human cervical cancer cells. Mol Biol Cell 2014 Oct 1;25(19):2905-2918.
  45. Millar AJ. Liver tumours in children: Current surgical management and role of transplantation. SAMJ: South African Medical Journal 2014;104(11):813-815.
  46. Murray, S.A. et al., 2014. Promoting palliative care in the community: Production of the primary palliative care toolkit by the European Association of Palliative Care Taskforce in primary palliative care. Palliative Medicine, 29(2), pp.101–111.
  47. Mutch D, Denny L, Quinn M. Hereditary gynecologic cancers. International Journal of Gynecology & Obstetrics 2014;124(3):189-192.
  48. Mutebi M, Edge J. Stigma, survivorship and solutions: Addressing the challenges of living with breast cancer in low-resource areas. SAMJ: South African Medical Journal 2014;104(5):382-382.
  49. Nakash O, Levav I, Aguilar‐Gaxiola S, Alonso J, Andrade LH, Angermeyer MC, et al. Comorbidity of common mental disorders with cancer and their treatment gap: findings from the World Mental Health Surveys. Psycho‐Oncology 2014;23(1):40-51.
  50. Noubiap JJ, Nansseu JR, Kengne KK, Wonkam A, Wiysonge CS. Low hepatitis B vaccine uptake among surgical residents in Cameroon. Int Arch Med 2014 Mar 14;7(1):11-7682-7-11.
  51. Paccez JD, Vogelsang M, Parker MI, Zerbini LF. The receptor tyrosine kinase Axl in cancer: biological functions and therapeutic implications. International Journal of Cancer 2014;134(5):1024-1033.​ 
  52. Parkes, J. et al., 2014. SIOP PODC adapted treatment recommendations for standard-risk medulloblastoma in low and middle income settings. Pediatric Blood & Cancer, 62(4), pp.553–564.
  53. Parkes JD, Davidson A, Figaji A. Improving the quality of care for children with brain tumours in South Africa: a report from the 4th Paediatric Brain Tumour Workshop: congress report. South African Journal of Child Health 2014;8(2):44-44.
  54. Powell RA, Harding R, Namisango E, Katabira E, Gwyther L, Radbruch L, et al. Palliative care research in Africa: Consensus building for a prioritized agenda. J Pain Symptom Manage 2014;47(2):315-324.
  55. Rawlinson F, Gwyther L, Kiyange F, Luyirika E, Meiring M, Downing J. The current situation in education and training of health-care professionals across Africa to optimise the delivery of palliative care for cancer patients. eCancer Medical Science 2014;8.
  56. Rice JC, Liebenberg L, Scholtz RP, Torr G. Fatal air embolism during endoresection of choroidal melanoma. Retin Cases Brief Rep 2014 Spring;8(2):127-129.​​
  57. Rohner E, Valeri F, Maskew M, Prozesky H, Rabie H, Garone D, et al. Incidence rate of Kaposi sarcoma in HIV-infected patients on antiretroviral therapy in Southern Africa: a prospective multicohort study. J Acquir Immune Defic Syndr 2014 Dec 15;67(5):547-554.​ 
  58. Sales KJ, Adefuye A, Nicholson L, Katz AA. CCR5 expression is elevated in cervical cancer cells and is up-regulated by seminal plasma. Mol Hum Reprod 2014 Nov;20(11):1144-1157.
  59. Sayed S, Moloo Z, Wasike R, Bird P, Oigara R, Govender D, et al. Is breast cancer from Sub Saharan Africa truly receptor poor? Prevalence of ER/PR/HER2 in breast cancer from Kenya. The Breast 2014;23(5):591-596.
  60. Schäfer G, Kaschula CH. The immunomodulation and anti-inflammatory effects of garlic organosulfur compounds in cancer chemoprevention. Anti-cancer agents in medicinal chemistry 2014;14(2):233.
  61. Senkus E, Gomez H, Dirix L, Jerusalem G, Murray E, Van Tienhoven G, et al. Attitudes of young patients with breast cancer toward fertility loss related to adjuvant systemic therapies. EORTC study 10002 BIG 3‐98. Psycho‐Oncology 2014;23(2):173-182.
  62. Sewram V, Sitas F, O’Connell D, Myers J. Diet and esophageal cancer risk in the Eastern Cape province of South Africa. Nutr Cancer 2014;66(5):791-799.​
  63. Shamley D, Lascurain‐Aguirrebeña I, Oskrochi R. Clinical anatomy of the shoulder after treatment for breast cancer. Clinical Anatomy 2014;27(3):467-477.
  64. Smit BJ, van Wijk AL. An improved, disposable indwelling intrauterine tube ("smit sleeve") not requiring retaining stitches for brachy-radiotherapy for carcinoma of the cervix. Eur J Gynaecol Oncol 2013;34(4):289-290.
  65. Spearman C, Sonderup MW. Preventing hepatitis B and hepatocellular carcinoma in South Africa: The case for a birth-dose vaccine. SAMJ: South African Medical Journal 2014;104(9):610-612.
  66. Stannard C, Maree G, Tovey S, Hunter A, Wetter J. Iodine-125 brachytherapy in the management of squamous cell carcinoma of the oral cavity and oropharynx. Brachytherapy 2014;13(4):405-412.
  67. Steffen J, Rice J, Lecuona K, Carrara H. Identification of ocular surface squamous neoplasia by in vivo staining with methylene blue. Br J Ophthalmol 2014 Jan;98(1):13-15.
  68. Stephenson KA, Lubbe DE. Primary Atypical Carcinoid Tumour of the Sphenoid Sinus Rostrum. Case reports in otolaryngology 2014;2014.
  69. Stupart D, Goldberg P, Algar U, Vorster A, Ramesar R. No evidence of genetic anticipation in a large family with Lynch syndrome. Familial cancer 2014;13(1):29-34.
  70. Stupart D, Win AK, Jenkins M, Winship IM, Goldberg P, Ramesar R. Fertility and apparent genetic anticipation in Lynch syndrome. Familial cancer 2014;13(3):369-374.
  71. Tashneem H. Endoscopic resection and postoperative Brachytherapy in the treatment of sinonasal melanoma. Journal of Case Reports in Medicine 2014;2014.
  72. Tathiah N, Moodley I, Denny L, Moodley J, Jassat W. Cervical cancer in South Africa: challenges and opportunities. South African Health Review 2013:117-125.​
  73. Van der Watt, Pauline J, Zemanay W, Govender D, Hendricks DT, Parker M, Leaner VD. Elevated expression of the nuclear export protein, Crm1 (exportin 1), associates with human oesophageal squamous cell carcinoma. Oncol Rep 2014;32(2):730-738.  
  74. van Niekerk L, Raubenheimer PJ. A point-prevalence survey of public hospital inpatients with palliative care needs in Cape Town, South Africa. SAMJ: South African Medical Journal 2014;104(2):138-141.
  75. Vegran F, Berger H, Boidot R, Mignot G, Bruchard M, Dosset M, et al. The transcription factor IRF1 dictates the IL-21-dependent anticancer functions of TH9 cells. Nat Immunol 2014 Aug;15(8):758-766.
  76. Vogelsang M, Paccez JD, Schäfer G, Dzobo K, Zerbini LF, Parker MI. Aberrant methylation of the MSH3 promoter and distal enhancer in esophageal cancer patients exposed to first-hand tobacco smoke. J Cancer Res Clin Oncol 2014;140(11):1825-1833.​ 
  77. Weaver MS, Hendricks M. A president who prioritized children: Applying Mandela's memory toward a global pediatric oncology future. Pediatric blood & cancer 2014;61(6):1145-1146.
  78. Wansleben S, Peres J, Hare S, Goding CR, Prince S. T-box transcription factors in cancer biology. Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 2014;1846(2):380-391.
  79. Yunusa GH, Kotze T, Brink A. Metastatic papillary carcinoma of the thyroid in a patient previously treated for Graves’ disease. Annals of African medicine 2014;13(2):91-94.​ 
  80. Zerbini LF, Bhasin MK, de Vasconcellos JF, Paccez JD, Gu X, Kung AL, et al. Computational repositioning and preclinical validation of pentamidine for renal cell cancer. Mol Cancer Ther 2014 Jul;13(7):1929-1941.